Fecal microbiota transplantation (FMT) is best described as which of the following?

• A. Transfer of stool from a healthy donor into the gut
• B. Oral antibiotics
• C. Surgical removal of colon
• D. Inhaled therapy

Answer: (A)

Fecal microbiota transplantation is about restoring the gut’s microbial community by introducing stool from a healthy donor into the recipient’s gut. This transfer brings a diverse mix of microbes that helps re-establish colonization resistance and balance after disruption, which is especially beneficial for recurrent Clostridioides difficile infection. It’s not simply taking antibiotics, removing the colon, or delivering medication by inhalation; those approaches don’t reintroduce a healthy microbial ecosystem into the gut. Deliveries can be via colonoscopy, enema, or oral capsules, but the defining idea is transferring healthy stool to repopulate the gut.