How do you perform a Fecal microbiota transplantation (FMT)?

• A. Transfer of stool from a healthy donor into the gut of the recipient
• B. Inhalation of aerosols containing gut bacteria
• C. Surgical transplantation of intestinal segments
• D. Oral antibiotic administration

Answer: (A)

Fecal microbiota transplantation involves transferring stool from a healthy, screened donor into the recipient’s gut to restore a diverse and balanced microbial community. The prepared donor stool is delivered directly to the gastrointestinal tract through methods that reach the gut, most commonly via colonoscopy, enema, or a tube from the upper GI tract, and increasingly as oral capsules. The goal is to reintroduce beneficial bacteria and microbial networks to outcompete pathogens and re-establish a healthy ecosystem in the intestine. This approach is not achieved by inhaling anything, by surgically transplanting intestinal tissue, or by using antibiotics alone, which do not move or replace the gut microbiota.