If cobalamin (B12) deficiency is found in a dog with PLE, what is the recommended action?

• A. No supplementation
• B. Initiate supplementation ASAP
• C. Delay treatment until symptoms worsen
• D. Dietary changes only

Answer: (B)

Cobalamin deficiency in a dog with PLE should be treated right away because B12 is essential for gut mucosal health, energy metabolism, and red blood cell production. In PLE, the ileum can be damaged or its function impaired, leading to poor B12 absorption; relying on diet alone won’t reliably correct the deficiency. Providing cobalamin promptly bypasses the absorption issue and helps support intestinal healing and overall condition. Parenteral (injected) B12 is commonly started to ensure reliable uptake, with monitoring and adjustment as the dog's status improves. Delaying treatment or using diet changes only does not address the deficiency quickly enough and can allow problems to worsen.